FORMULATION

Each film coated tablet contains:
Olmesartan medoxomil  20mg
Amlodipine besilate 5mg

Each film coated tablet contains:
Olmesartan medoxomil   20mg
Amlodipine besilate  10mg

Each film coated tablet contains:
Olmesartan medoxomil   40mg
Amlodipine besilate   5mg

Each film coated tablet contains:
Olmesartan medoxomil 40mg
Amlodipine besilate  10mg

INDICATIONS

Olmesartan medoxomil plus Amlodipine besilate is indicated for the treatment of hypertension, alone or with other antihypertensive agents.

This fixed combination drug is not indicated for the initial therapy of hypertension (see DOSAGE AND ADMINISTRATION)

CONTRAINDICATIONS

Patients with known hypersensitivity to Olmesartan medoxomil, Amlodipine besilate or any of its components.

DOSAGE AND ADMINISTRATION

General Considerations

The side effects of Olmesartan medoxomil are generally rare and apparently independent of dose.

Those of Amlodipine are generally dose-dependent (mostly edema).

Maximum antihypertensive effects are attained within 2 weeks after a change in dose.

Olmesartan medoxomil plus Amlodipine besilate may be taken with or without food.

Olmesartan medoxomil plus Amlodipine besilate may be administered with other antihypertensive agents.

Dosage may be increased after 2 weeks. The maximum recommended dose of Olmesartan medoxomil plus Amlodipine besilate is 40/10 mg.

Replacement Therapy

Olmesartan medoxomil plus Amlodipine besilate may be substituted for its individually titrated components.

When substituting for individual components, the dose of one or both of the components can be increased if blood pressure control has not been satisfactory.

Add-on Therapy for Patients with Hypertension Not Adequately Controlled on Amlodipine or Olmesartan Medoxomil Alone

Olmesartan medoxomil plus Amlodipine besilate may be used as add-on therapy for patients not adequately controlled on Amlodipine or Olmesartan medoxomil.

CAUTION:

Foods, Drugs, Devices and Cosmetics Act prohibits dispensing without prescription.

FULL PRESCRIBING INFORMATION AVAILABLE ON REQUEST